Title:
低刺激性アレルゲン
Document Type and Number:
Japanese Patent JP2014515752
Kind Code:
A
Abstract:
The present invention provides mutant polypeptides useful as hypoallergens. More specifically the present invention provides mutant Bet v 1 proteins and the use of such polypeptides as hypoallergens for desensitizing against birch pollen allergies. Furthermore, the invention provides vaccine formulations comprising such polypeptides; the use of such formulations; and to methods of vaccination against birch pollen allergy.
Inventors:
Takkinen, Christina
Laukkanen, Maruja Lena
Sederlund, Hans
Jilhe, Silpa
Holkeli, Haydy
Niemi, Melya
Jennes, Yannes
Rowbinen, Juha
Laukkanen, Maruja Lena
Sederlund, Hans
Jilhe, Silpa
Holkeli, Haydy
Niemi, Melya
Jennes, Yannes
Rowbinen, Juha
Application Number:
JP2014505596A
Publication Date:
July 03, 2014
Filing Date:
April 18, 2012
Export Citation:
Assignee:
Technoan totokimus quescus buitity
International Classes:
C07K14/415; A61K39/36; A61K39/39; A61P37/08; C12N15/09
Domestic Patent References:
| JP2004521618A | 2004-07-22 |
Foreign References:
| WO2003096869A2 | 2003-11-27 |
Attorney, Agent or Firm:
Kurata Masatoshi
Yoshihiro Fukuhara
Nobuhisa Nogawa
Takashi Mine
Katsu Sunagawa
Yoshihiro Fukuhara
Nobuhisa Nogawa
Takashi Mine
Katsu Sunagawa