Title:
抗癌治療及び画像化並びに骨障害治療のための金属ビスホスホネートナノ粒子
Document Type and Number:
Japanese Patent JP2014520849
Kind Code:
A
Abstract:
Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate nanoparticles and materials comprising the nanoparticles, and methods of using the compositions to treat cancer or bone-related disorders (e.g., bone-resorption-related diseases, osteoporosis, Paget's disease, and bone metastases) and as imaging agents.
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Inventors:
ウェンビン Lynn
デミン リォウ
Joseph デラロッカ
Stephanie Ey Kramer
Christopher Wai Poon
デミン リォウ
Joseph デラロッカ
Stephanie Ey Kramer
Christopher Wai Poon
Application Number:
JP2014520238A
Publication Date:
August 25, 2014
Filing Date:
July 09, 2012
Export Citation:
Assignee:
ザユニ bar city オブ North Carolina アット Chapel Hill THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
International Classes:
A61K31/663; A61K9/107; A61K9/127; A61K9/14; A61K9/51; A61K31/282; A61K31/713; A61K38/00; A61K41/00; A61K45/00; A61K47/04; A61K47/18; A61K47/24; A61K49/00; A61K51/00; A61P19/08; A61P35/00
Domestic Patent References:
| JP2007521257A | 2007-08-02 | |||
| JP2008533173A | 2008-08-21 | |||
| JP2010534202A | 2010-11-04 | |||
| JP2006517182A | 2006-07-20 | |||
| JP2008530200A | 2008-08-07 | |||
| JP2007521257A | 2007-08-02 |
Foreign References:
| WO2009008345A1 | 2009-01-15 | |||
| WO2010065751A2 | 2010-06-10 | |||
| WO2008016172A1 | 2008-02-07 | |||
| WO2009008345A1 | 2009-01-15 |
Other References:
JPN6016011186; Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｊｏｕｒｎａｌ ｏｆ Ｐｈａｒｍａｃｅｕｔｉｃｓ Ｖｏｌ．４０３, 2010, ｐ．２９２-２９７
Attorney, Agent or Firm:
Shimoda Showa
Ken-ichiro Akao
Kazuhiko Kurihara
Ken-ichiro Akao
Kazuhiko Kurihara