Title:
２−アミノ−４−（ピリジン−２−イル）−５，６−ジヒドロ−４Ｈ−１，３−オキサジン誘導体およびＢＡＣＥ−１および／またはＢＡＣＥ−２阻害剤としてのそれらの使用
Document Type and Number:
Japanese Patent JP2014524463
Kind Code:
A
Abstract:
The invention relates to novel oxazine derivatives of formula (I), and pharmaceutically acceptable salts thereof,
in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease via inhibition of BACE-1.
Inventors:
The Reiner Martin リュエント
Liner Mach オアー
Heinrich リューガー
Sime Jacob Veenstra
Liner Mach オアー
Heinrich リューガー
Sime Jacob Veenstra
Application Number:
JP2014526591A
Publication Date:
September 22, 2014
Filing Date:
August 23, 2012
Export Citation:
Assignee:
Novartis アーゲー
International Classes:
C07D413/14; A61K31/5355; A61K45/00; A61P3/04; A61P3/10; A61P5/50; A61P9/12; A61P25/28; A61P43/00
Attorney, Agent or Firm:
Yamada Takuji
Aoyama 葆
Michiko Matsutani
Mitsutaka Iwasaki
Ochiai 康
Aoyama 葆
Michiko Matsutani
Mitsutaka Iwasaki
Ochiai 康
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