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Title:
ＡＬＫ１阻害剤としてのヒドロキシメチルアリール−置換ピロロトリアジン
Document Type and Number:
Japanese Patent JP2014525902
Kind Code:
A
Abstract:
This invention relates to novel 5-[(hydroxymethyl)aryl]-substituted pyrrolo[2,1-f][1,2,4]triazin-4-amines of formula (I), to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating angiogenesis-related disorders, in particular angiogenesis-related ocular disorders.

Inventors:
Jurgen クラー
フェレーナ Fehringer
Joachim テルザー
Mario ロベル
Frank juice Mayer
Volk ハルト Min * Ian Li
Michael Bettger
Stefan Goltz
Dieter Lang
Curl * Heinz Schlemmer
Thomas シュランゲ
Andreas Shal
フ ウェンラン
Application Number:
JP2014517662A
Publication Date:
October 02, 2014
Filing Date:
June 26, 2012
Export Citation:
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Assignee:
Beyer intellectual property gesellschaft mitt ベシュレンクテル ハフツング Bayer Intellectual Property GmbH
Beyer ファルマ Aktiengesellschaft Bayer Pharma Aktiengesellschaft
International Classes:
C07D487/04; A61K31/53; A61K31/5377; A61K45/00; A61P9/00; A61P9/10; A61P27/02; A61P43/00; C07B61/00
Domestic Patent References:
JP2009541242A2009-11-26
JP2009506993A2009-02-19
JP2010508315A2010-03-18
JP2010534633A2010-11-11
JP2011500623A2011-01-06
JP2009515995A2009-04-16
JP2009514882A2009-04-09
JP2009518303A2009-05-07
JP2003500359A2003-01-07
JP2009541242A2009-11-26
JP2009506993A2009-02-19
JP2010508315A2010-03-18
JP2010534633A2010-11-11
JP2011500623A2011-01-06
JP2009515995A2009-04-16
JP2009514882A2009-04-09
JP2009518303A2009-05-07
JP2003500359A2003-01-07
Foreign References:
WO2009140128A22009-11-19
WO2009140128A22009-11-19
Attorney, Agent or Firm:
Yamada Takuji
Aoyama 葆
Michiko Matsutani
Satoshi Hashimoto
Ochiai 康



 
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