Title:
慢性腎臓病患者の治療におけるクエン酸第二鉄の使用
Document Type and Number:
Japanese Patent JP2015535209
Kind Code:
A
Abstract:
慢性腎臓病患者において、血清リンレベルを低下させ及び/もしくは制御し、血清重炭酸塩レベルを増加させ、1以上の鉄貯蔵パラメータを改善し(例えば、血清フェリチンレベルを増加させ、トランスフェリン飽和度(TSAT)を増加させ、ヘモグロビン濃度を増加させ)、鉄吸収を増加させ、鉄貯蔵を維持し、鉄欠乏を治療し、貧血を治療し、IV鉄の必要性を低下させ、並びに/又は赤血球生成刺激剤(ESA)の必要性を低下させるために、クエン酸第二鉄を投与する方法が開示されている。【選択図】なし
More Like This:
Inventors:
Enrique Polados
Ron Benthul
James F. Olivier third
Ron Benthul
James F. Olivier third
Application Number:
JP2015518623A
Publication Date:
December 10, 2015
Filing Date:
June 21, 2013
Export Citation:
Assignee:
Kerik By Offer Mathewicals, Incorporated
International Classes:
A61K31/194; A61K9/20; A61P3/00; A61P7/06; A61P7/08; A61P13/12; A61P17/00; A61P17/14; A61P25/00; A61P37/02
Domestic Patent References:
| JP2001506262A | 2001-05-15 | |||
| JP2009525276A | 2009-07-09 |
Other References:
AM J NEPHROL, vol. 36, JPN6017008904, 2012, pages 478 - 487, ISSN: 0003519704
NEPHROL DIAL TRANSPLANT, vol. 17, JPN6017008905, 2002, pages 265 - 270, ISSN: 0003519705
AM J KIDNEY DIS., vol. 57, no. 4, JPN6017008907, 2011, pages 89 - 292, ISSN: 0003699738
NEPHROLOGY DIALYSIS TRANSPLANTATION, vol. Vol.27, Suppl. 2, JPN7017000907, May 2012 (2012-05-01), pages 490 - 536, ISSN: 0003699739
KIDNEY RES CLIN PRACT, vol. 31, JPN6017008909, 20 June 2012 (2012-06-20), pages 38 - 90, ISSN: 0003699740
VALUE IN HEALTH, vol. 15, no. 4, JPN6017008911, 2 June 2012 (2012-06-02), pages 155 - 16, ISSN: 0003699741
"Trial of a new formulation of KRX-0502(Ferric citrate) in patients with end-stage renal disease", CLINICALTRIALS.GOV ARCHIVE, JPN6017008913, 2 June 2010 (2010-06-02), ISSN: 0003519710
"A 4-week dose-ranging and efficacy trial of KRX-0502(Ferric Citrate) in patients with end-stage rena", CLINICALTRIALS.GOV.ARCHIVE, JPN6017008914, 4 January 2011 (2011-01-04), ISSN: 0003519711
"エビデンスに基づくＣＫＤ診療ガイドライン２００９", 日本腎臓学会誌, vol. ５１巻，８号, JPN6017047399, 2009, pages 955 - 957, ISSN: 0003699744
"慢性腎臓病患者における腎性貧血治療のガイドライン", 日本透析学会雑誌, vol. ４１巻、１０号, JPN6017047398, 2008, pages 662 - 716, ISSN: 0003699745
NEPHROL DIAL TRANSPLANT, vol. 17, JPN6017008905, 2002, pages 265 - 270, ISSN: 0003519705
AM J KIDNEY DIS., vol. 57, no. 4, JPN6017008907, 2011, pages 89 - 292, ISSN: 0003699738
NEPHROLOGY DIALYSIS TRANSPLANTATION, vol. Vol.27, Suppl. 2, JPN7017000907, May 2012 (2012-05-01), pages 490 - 536, ISSN: 0003699739
KIDNEY RES CLIN PRACT, vol. 31, JPN6017008909, 20 June 2012 (2012-06-20), pages 38 - 90, ISSN: 0003699740
VALUE IN HEALTH, vol. 15, no. 4, JPN6017008911, 2 June 2012 (2012-06-02), pages 155 - 16, ISSN: 0003699741
"Trial of a new formulation of KRX-0502(Ferric citrate) in patients with end-stage renal disease", CLINICALTRIALS.GOV ARCHIVE, JPN6017008913, 2 June 2010 (2010-06-02), ISSN: 0003519710
"A 4-week dose-ranging and efficacy trial of KRX-0502(Ferric Citrate) in patients with end-stage rena", CLINICALTRIALS.GOV.ARCHIVE, JPN6017008914, 4 January 2011 (2011-01-04), ISSN: 0003519711
"エビデンスに基づくＣＫＤ診療ガイドライン２００９", 日本腎臓学会誌, vol. ５１巻，８号, JPN6017047399, 2009, pages 955 - 957, ISSN: 0003699744
"慢性腎臓病患者における腎性貧血治療のガイドライン", 日本透析学会雑誌, vol. ４１巻、１０号, JPN6017047398, 2008, pages 662 - 716, ISSN: 0003699745
Attorney, Agent or Firm:
Toru Ishikawa