Title:
抗ＬＡＧ−３結合タンパク質
Document Type and Number:
Japanese Patent JP2016516681
Kind Code:
A
Abstract:
リンパ球活性化遺伝子3（LAG-3）に結合する抗原結合タンパク質、より具体的にはLAG-3+活性化T細胞の枯渇を生じる抗原結合タンパク質に関する。【選択図】なし
Inventors:
Hamburg, Paul Andrew
Lewis, Alan Peter
Web, thomas matthew
Lewis, Alan Peter
Web, thomas matthew
Application Number:
JP2015562153A
Publication Date:
June 09, 2016
Filing Date:
March 13, 2014
Export Citation:
Assignee:
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
International Classes:
C07K14/00; A61K38/00; A61K39/395; A61P1/00; A61P1/16; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P31/00; A61P35/00; A61P37/02; A61P37/06; A61P37/08; C07K7/00; C07K16/28; C07K16/42; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09
Domestic Patent References:
| JP2010526052A | 2010-07-29 | |||
| JP2012500006A | 2012-01-05 |
Other References:
POIRIER N ET AL: "Antibody-mediated depletion of lymphocyte-activation gene-3 (LAG-3(+) )-activated T lymphocytes prev", CLIN EXP IMMUNOL., vol. 164, JPN6016033733, May 2011 (2011-05-01), pages 265 - 274, XP055055512, ISSN: 0003395196, DOI: 10.1111/j.1365-2249.2011.04329.x
安田修平他: "抗体のＣＤＲグラフティング", 血栓止血誌, vol. 4, JPN6016033737, 1993, pages 193 - 200, ISSN: 0003395197
杉村和久他: "ファージディスプレイとヒト抗体エンジニアリング", ドージンニュース, JPN6016033739, 23 January 2004 (2004-01-23), pages 1 - 7, ISSN: 0003395198
橋口周平他: "ファージディスプレイとBeyond antibody", 生化学, vol. 第82巻,第8号, JPN6016033740, 2010, pages 710 - 726, ISSN: 0003395199
YAMANE-OHNUKI N. ET AL: "Establishment of FUT8 knockout Chinese hamster ovary cells: an ideal host cell line for producing co", BIOTECHNOL BIOENG., vol. 87, no. 5, JPN6016033735, 6 August 2004 (2004-08-06), pages 615 - 622, ISSN: 0003395200
安田修平他: "抗体のＣＤＲグラフティング", 血栓止血誌, vol. 4, JPN6016033737, 1993, pages 193 - 200, ISSN: 0003395197
杉村和久他: "ファージディスプレイとヒト抗体エンジニアリング", ドージンニュース, JPN6016033739, 23 January 2004 (2004-01-23), pages 1 - 7, ISSN: 0003395198
橋口周平他: "ファージディスプレイとBeyond antibody", 生化学, vol. 第82巻,第8号, JPN6016033740, 2010, pages 710 - 726, ISSN: 0003395199
YAMANE-OHNUKI N. ET AL: "Establishment of FUT8 knockout Chinese hamster ovary cells: an ideal host cell line for producing co", BIOTECHNOL BIOENG., vol. 87, no. 5, JPN6016033735, 6 August 2004 (2004-08-06), pages 615 - 622, ISSN: 0003395200
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Naoko Kikuta
Satoko Tsuruta
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Naoko Kikuta
Satoko Tsuruta