Title:
ＣＤ３／ＣＤ３８ Ｔ細胞再標的化ヘテロ二量体免疫グロブリン及びその製造方法
Document Type and Number:
Japanese Patent JP2018501297
Kind Code:
A
Abstract:
本発明は、ヒトＣＤ３抗原の成分とヒトＣＤ３８抗原の成分の両方を標的とするヘテロ二量体免疫グロブリン及びその製造方法に関する。本発明はまた、治療用又は診断用試薬としての使用のための、ヒトＣＤ３８抗原及びその誘導体に結合する抗体並びにその製造方法に関する。【選択図】なし
Inventors:
Orie, romance
Wu, Samuel
Licilla
Skeguro, Darco
Back, Jonathan
Wu, Samuel
Licilla
Skeguro, Darco
Back, Jonathan
Application Number:
JP2017542319A
Publication Date:
January 18, 2018
Filing Date:
November 03, 2015
Export Citation:
Assignee:
Glen Mark Pharmaceuticals, Ese.
International Classes:
C07K16/46; A61K39/395; A61K47/68; A61P3/00; A61P35/00; A61P35/02; A61P43/00; C07K16/28
Domestic Patent References:
| JP2010506582A | 2010-03-04 | |||
| JP2014509837A | 2014-04-24 | |||
| JP2013539352A | 2013-10-24 | |||
| JP2008504013A | 2008-02-14 |
Other References:
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ELLIS JONATHAN H; ET AL: "ENGINEERED ANTI-CD38 MONOCLONAL ANTIBODIES FOR IMMUNOTHERAPY OF MULTIPLE MYELOMA", THE JOURNAL OF IMMUNOLOGY, vol. VOL:155, NR:2, JPN5017009105, 1995, US, pages 925 - 937, ISSN: 0004184116
EXPERT OPIN. DRUG DISCOV., 2008, 3(9), PP.1081-1097, JPN6019006012, ISSN: 0004184117
J. IMMUNOL., 1998, VOL.161, P.4702-4708, JPN6018017743, ISSN: 0004184118
Attorney, Agent or Firm:
Sonoda/Kobayashi Patent Business Corporation