Title:
ヒトＣＤ４０に特異的に結合するアンタゴニスト抗体及び使用方法
Document Type and Number:
Japanese Patent JP2018529351
Kind Code:
A
Abstract:
本発明は、ヒトＣＤ４０に特異的に結合するアンタゴニスト抗体、この抗体又はその抗原結合断片をコードするポリヌクレオチド、及び前述のものを作製及び使用する方法に関する。
Inventors:
Babe, Holger
Felix, Nathan
Franson, Joan
Kim paul
Scully, Michael
Zou, Hong
Felix, Nathan
Franson, Joan
Kim paul
Scully, Michael
Zou, Hong
Application Number:
JP2018516413A
Publication Date:
October 11, 2018
Filing Date:
September 30, 2016
Export Citation:
Assignee:
Janssen Biotech, Inc.
International Classes:
C12N15/13; A61K31/4706; A61K31/573; A61K31/60; A61K31/635; A61K39/395; A61K45/00; A61P1/04; A61P1/16; A61P3/10; A61P7/00; A61P9/10; A61P13/12; A61P17/00; A61P17/06; A61P19/00; A61P19/02; A61P21/04; A61P25/00; A61P29/00; A61P37/06; C07K16/28; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/08
Domestic Patent References:
| JP2009022289A | 2009-02-05 | |||
| JP2018533360A | 2018-11-15 |
Foreign References:
| WO2012065950A1 | 2012-05-24 | |||
| WO2015134988A1 | 2015-09-11 | |||
| WO2011123489A2 | 2011-10-06 |
Other References:
GOLDWATER, R, ET AL: "A Phase 1, Randomized Ascending Single-Dose Study of Antagonist Anti-Human CD40 ASKP1240 in Healthy", AMERICAN JOURNAL OF TRANSPLANTATION, vol. 13, JPN6020029022, 2013, pages 1040 - 1046, XP055577283, ISSN: 0004462096, DOI: 10.1111/ajt.12082
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Junko Kobayashi
Ryo Hoshikawa
Yasuhito Suzuki
Eiji Katayama
Norio Omori
Junko Kobayashi
Ryo Hoshikawa
Yasuhito Suzuki