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Title:
NOVEL ANALOG OF EPICATECHIN AND RELATED POLYPHENOL
Document Type and Number:
Japanese Patent JP2019034944
Kind Code:
A
Abstract:
To provide a novel analog of polyphenol and a preparation method therefor.SOLUTION: There is provided an analog of epicatechin polyphenol represented by the following formula, wherein A is independently deuterium, hydrogen, alkyl, F, Cl; B is independently A or hydroxyl; ORand NRR.SELECTED DRAWING: None

Inventors:
SUNDEEP DUGAR
DINESH MAHAJAN
KUMAR SANTOSH RAI
SARBJIT SINGH
ISHWAR RAKESH PATIL
Application Number:
JP2018180509A
Publication Date:
March 07, 2019
Filing Date:
September 26, 2018
Export Citation:
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Assignee:
SPHAERA PHARMA PRIVATE LTD
International Classes:
C07D311/60; A23L33/10; A61K31/353; A61P21/00; A61P43/00; C07D311/62
Domestic Patent References:
JP2012524077A2012-10-11
JP2011503171A2011-01-27
JP2008505657A2008-02-28
JPH06279430A1994-10-04
JP2001131169A2001-05-15
JP2009501706A2009-01-22
Foreign References:
WO2013022846A22013-02-14
CN102578094A2012-07-18
WO2012101652A22012-08-02
WO2013020979A12013-02-14
US3689663A1972-09-05
Other References:
AUSTRALIAN JOURNAL OF CHEMISTRY, vol. 26, JPN6019026595, 1973, pages 2675 - 2682, ISSN: 0004073178
J. LABEL. COMPD. RADIOPHARM., vol. 52, JPN6019026597, 2009, pages 312 - 315, ISSN: 0004073179
BIOORG. MED. CHEM., vol. 17, JPN6019026599, 2009, pages 7156 - 7173, ISSN: 0004073180
J. CHEM. SOC., PERKIN TRANS. 1, JPN6019026600, 1997, pages 3415 - 3421, ISSN: 0004073181
FERRARI, GABRIELA V. ET AL.: "Novel Synthesis of 3,3'-Dihydroxyflavone and Apparent Formation Constants of Flavonoid-Ga(III) Compl", JOURNAL OF CHEMICAL & ENGINEERING DATA, vol. 55(9), JPN6018010392, 2010, pages 3080 - 3083, ISSN: 0004363501
LI, Z. ET AL.: "Synthesis of a library of glycosylated flavonols", TETRAHEDRON LETTERS, vol. 49(51), JPN6018010382, 2008, pages 7243 - 7245, ISSN: 0004363500
Attorney, Agent or Firm:
Shinichiro Tanaka
Disciple Maru Ken
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Akizawa