Title:
DETECTION SYSTEM AND METHOD FOR HIGH-SENSITIVITY FLUOROMETRIC ANALYSIS
Document Type and Number:
Japanese Patent JP2019048986
Kind Code:
A
Abstract:
To provide a detection system for measuring a fluorescence signal in a fluorometric analysis.SOLUTION: This system includes a probe having a small sensing face connected to a fluorescent label, and a light source and a detector respectively attached to a side closer to a sensing face of a substrate. The invention also relates to a method of detecting an analyte inside a liquid sample using a probe chip having a small surface (≤5 mm), and a high molecular weight polymer (≥1MD) having a plurality of binding molecules and a plurality of fluorescent labels. A binding reaction is accelerated by flowing a reaction solution in a horizontal direction while moving the probe chip vertically in a reaction vessel. The invention also relates to a fluorescent label mixture including a cross-linkage ficoll having a plurality of binding molecules and a plurality of fluorescent labels.SELECTED DRAWING: Figure 1
Inventors:
TANG HONG
ROBERT F ZUK
TAN YUSHAN
CAO ERHUA
XIA MIN
CHEN JUN
ROBERT F ZUK
TAN YUSHAN
CAO ERHUA
XIA MIN
CHEN JUN
Application Number:
JP2018195316A
Publication Date:
March 28, 2019
Filing Date:
October 16, 2018
Export Citation:
Assignee:
ACCESS MEDICAL SYSTEMS LTD
International Classes:
C08G65/334
Domestic Patent References:
| JPH11511558A | 1999-10-05 | |||
| JP2009531302A | 2009-09-03 | |||
| JPH02243617A | 1990-09-27 | |||
| JP2004537535A | 2004-12-16 |
Foreign References:
| US5650334A | 1997-07-22 |
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mitsuhashi
Tomohiro Minamiyama
Koichi Itsubo
Shinji Mitsuhashi
Tomohiro Minamiyama
Koichi Itsubo