Title:
METHODS FOR SCREENING ANTIBODIES
Document Type and Number:
Japanese Patent JP2019167339
Kind Code:
A
Abstract:
To provide an improved method for screening antibodies for use as antibody drug conjugates (ADC).SOLUTION: The present invention provides methods for making antibody conjugates for use in antibody screening assays and antibody conjugates to be produced by methods described within a range of patent claims. In one aspect, the methods comprise the steps of: providing a first and second antibody-containing sample, in which the first and second antibody-containing sample vary with respect to an antibody quantity and an antibody sequence, provided that substantially all of the antibodies present in the first sample is of the same sequence and substantially all of the antibodies present in the second sample is of the same sequence; and immobilizing the antibodies on an immobilization support to provide a first and second sample including immobilized antibodies.SELECTED DRAWING: Figure 11
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Inventors:
ROBERT LYON
DENNIS BENJAMIN
MAUREEN RYAN
DENNIS BENJAMIN
MAUREEN RYAN
Application Number:
JP2019060059A
Publication Date:
October 03, 2019
Filing Date:
March 27, 2019
Export Citation:
Assignee:
SEATTLE GENETICS INC
International Classes:
A61K47/68; A61K9/44; A61K38/05; A61K39/395; A61P35/00; C12P21/02; G01N33/15; G01N33/50
Domestic Patent References:
| JP2005530143A | 2005-10-06 | |||
| JP2006500333A | 2006-01-05 | |||
| JPH06256216A | 1994-09-13 |
Foreign References:
| WO2009099719A2 | 2009-08-13 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita