Title:
METHODS AND PROBES FOR DETECTING ESOPHAGEAL CANCER
Document Type and Number:
Japanese Patent JP2019213542
Kind Code:
A
Abstract:
To provide description of probe sets and methods of using probes and probe sets for selectively detecting high grade dysplasia and esophageal adenocarcinoma or low grade dysplasia.SOLUTION: Methods of the invention include contacting a biological sample obtained from a subject with a set of chromosomal probes to selectively detect an esophageal carcinoma or precursor lesion in the sample, if any, under conditions for specifically hybridizing the probes to their nucleic targets present in the sample. The presence or absence of high grade dysplasia and esophageal adenocarcinoma or low grade dysplasia is thereafter specifically determined from the hybridization pattern detected for the set of chromosomal probes to the biological sample.SELECTED DRAWING: Figure 1A
Inventors:
KEVIN HALLING
MORRISON LARRY E
SHANNON BRANKLEY
MORRISON LARRY E
SHANNON BRANKLEY
Application Number:
JP2019142115A
Publication Date:
December 19, 2019
Filing Date:
August 01, 2019
Export Citation:
Assignee:
ABBOTT MOLECULAR INC
MAYO FOUND FOR MEDICAL EDUCATION & RES
MAYO FOUND FOR MEDICAL EDUCATION & RES
International Classes:
C12Q1/6813; C12Q1/6886; G01N33/53; G01N33/58
Attorney, Agent or Firm:
Patent business corporation Odashima patent office