Title:
CARTRIDGE AND METHOD FOR INCREASING MYOCARDIAL FUNCTION
Document Type and Number:
Japanese Patent JP2020072825
Kind Code:
A
Abstract:
To provide a method to be used in a method of increasing the myocardial function of a subject with chronic heart failure.SOLUTION: The method comprises: introducing, into a cartridge 100 having a solid support 120 defining a fluid contacting surface with a surface area capable of sequestering activated leukocytes and/or activated platelets, if present in a body fluid, a body fluid through a fluid inlet port 114 under conditions that permit sequestration of the activated leukocytes and/or activated platelets on the fluid contacting surface of the solid support; and treating the sequestered leukocytes and/or platelets to inhibit release of a pro-inflammatory substance or to deactivate the leukocytes and/or platelets.SELECTED DRAWING: Figure 1A
Inventors:
H DAVID HUMES
DEBORAH A BUFFINGTON
DEBORAH A BUFFINGTON
Application Number:
JP2019181842A
Publication Date:
May 14, 2020
Filing Date:
October 02, 2019
Export Citation:
Assignee:
H DAVID HUMES
DEBORAH A BUFFINGTON
DEBORAH A BUFFINGTON
International Classes:
A61K35/15; A61M1/36; A61K35/19; A61P9/04; C12M1/26
Domestic Patent References:
| JP2010538973A | 2010-12-16 | |||
| JP2008136757A | 2008-06-19 | |||
| JP2001149471A | 2001-06-05 |
Foreign References:
| US20040142463A1 | 2004-07-22 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto