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Title:
METHOD FOR PREDICTING ONSET OF EXTRAPYRAMIDAL SYMPTOMS (EPS) INDUCED BY ANTIPSYCHOTIC-BASED TREATMENT
Document Type and Number:
Japanese Patent JP2020089370
Kind Code:
A
Abstract:
To provide methods for predicting the onset of extrapyramidal symptoms (EPSs) induced by an antipsychotic-based treatment, and methods for providing personalized medicine to patients based on the sequence of several SNPs associated with the onset of the EPSs.SOLUTION: A method for predicting the onset of extrapyramidal symptoms (EPSs) induced by an antipsychotic-based treatment in a subject comprises i) determining the sequence of the rs1130214, rs456998, rs7211818 and rs1053639 single nucleotide polymorphisms (SNPs) in a sample comprising genetic material from the subject, and ii) predicting the risk of the subject developing the EPSs based on the sequence of the SNPs.SELECTED DRAWING: None

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Inventors:
SERGI MAS HERRERO
PATRICIA GASSO ASTORGA
CRISTINA MALAGELADA GRAU
MIQUEL BERNARDO ARROYO
AMALIA LAFUENTE FLO
Application Number:
JP2020000418A
Publication Date:
June 11, 2020
Filing Date:
January 06, 2020
Export Citation:
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Assignee:
UNIV BARCELONA
HOSPITAL CLINIC BARCELONA
INSTITUT DE INVESTIG BIOMEDIQUES AUGUST PI I SUNYER
CENTRO DE INVESTIG BIOMEDICA EN RED CIBER
International Classes:
C12Q1/6827; A61K45/00; A61K45/06; A61P25/16; A61P25/18; A61P43/00; C12Q1/6876; G01N33/50
Attorney, Agent or Firm:
Noritaka Yokota
Enoki Yasutaka
Omori Miko