PROCESSES FOR PRODUCING STABLE EXOSOME FORMULATIONS

Title:

PROCESSES FOR PRODUCING STABLE EXOSOME FORMULATIONS

Document Type and Number:

Japanese Patent JP2020138983

Kind Code:

A

Abstract:

To provide stable exosome formulations.SOLUTION: A stable lyophilized exosome formulation suitable for administration to a human comprises at least 106 exosomes, where the lyophilized exosomes maintain at least 90% of the levels of miR-210 RNA and miR-146A of the exosome formulation before the lyophilization.SELECTED DRAWING: None

Inventors:

KREKE MICHELLE
RACHEL SMITH
PETER HANSCOME
KIEL PECK
AHMED IBRAHIM

Application Number:

JP2020101158A

Publication Date:

September 03, 2020

Filing Date:

June 10, 2020

Export Citation:

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Assignee:

CAPRICOR INC

International Classes:

A61K35/12; A61K9/10; A61K9/19; A61K31/7105; A61K35/34; A61K48/00; A61P9/00

Domestic Patent References:

JPH07507460A	1995-08-24
JP2013523823A	2013-06-17
JP2014507482A	2014-03-27

Foreign References:

WO2014028493A2

2014-02-20

Attorney, Agent or Firm:

Ryoichi Takaoka
Nao Oda
Akiyo Iwahori
Kaoru Takahashi

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