Title:
NONAROMATIC HETEROCYCLE DERIVATIVES HAVING MGAT2 INHIBITORY ACTIVITY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
Document Type and Number:
Japanese Patent JP2020158390
Kind Code:
A
Abstract:
To provide pharmaceutical compositions containing tetrahydropyridine derivatives having monoacylglycerol acyltransferase 2 (MGAT2) inhibitory action.SOLUTION: A pharmaceutical composition contains a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. (In the formula, X and Z are C(=O) or the like; L is a single bond, O, S, or the like; R is R6, B, or the like; A and B are each independently an aromatic carbocycle or the like; R2 is H or the like; R3 is alkyl or the like; R4a and R4b are each independently H or the like; R5 and R6 are halogen or the like; R7a is H or the like; R7b, R8 and R9 are H or the like; m and n are integers from 0 to 5; and p is an integer from 1 to 6.)SELECTED DRAWING: None
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Inventors:
KURAHASHI KANA
NISHIURA YUJI
OYABU NAOKI
SASAKI YOSHIKAZU
NISHIURA YUJI
OYABU NAOKI
SASAKI YOSHIKAZU
Application Number:
JP2017120052A
Publication Date:
October 01, 2020
Filing Date:
June 20, 2017
Export Citation:
Assignee:
SHIONOGI & CO
International Classes:
A61K31/4418; A61K31/444; A61K31/501; A61K31/506; A61K31/5377; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P43/00; C07D211/86; C07D401/04; C07D413/14
Attorney, Agent or Firm:
Kenichi Sugita