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Title:
METHOD AND INTERMEDIATE FOR PRODUCING ISOMER-FREE PROSTAGLANDIN
Document Type and Number:
Japanese Patent JP2020164527
Kind Code:
A
Abstract:
To provide prostaglandins that are substantially free of 5,6-trans isomer.SOLUTION: A composition contains a prostaglandin derivative. A composition contains travoprost free acid, in which the 5,6-trans isomer content is less than 0.1% and the 15β isomer content is less than 0.1%. A composition contains latanoprost free acid, in which the 5,6-trans isomer content is less than 0.1% and the 15β isomer content is less than 0.1%. A composition contains tafluprost free acid, in which the 5,6-trans isomer content is less than 0.1%.SELECTED DRAWING: None

Inventors:
WEI SHIH-YI
YEH YU-CHIH
HSU MIN-KUAN
KAO LI-TA
Application Number:
JP2020069562A
Publication Date:
October 08, 2020
Filing Date:
April 08, 2020
Export Citation:
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Assignee:
CHIROGATE INT INC
International Classes:
C07C405/00
Domestic Patent References:
JP2009500315A2009-01-08
JP2015036382A2015-02-23
JP2016193930A2016-11-17
JP2018140990A2018-09-13
JP2012530783A2012-12-06
Foreign References:
US20050209337A12005-09-22
WO2013093528A12013-06-27
WO2011095990A22011-08-11
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation