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Title:
FOOT-AND-MOUTH DISEASE VACCINE
Document Type and Number:
Japanese Patent JP2021001205
Kind Code:
A
Abstract:
To provide compositions for prevention of foot-and-mouth disease (FMD).SOLUTION: An immunogenic composition comprises an antigen component and an adjuvant component, where: a) the adjuvant component comprises an emulsion containing oil, an immunostimulatory oligonucleotide, and at least one of i) a polycationic polymer and ii) a source of aluminum; and b) the antigen component comprises 0.5-10 μg of an FMD virus composition per dose.SELECTED DRAWING: Figure 1

Inventors:
PAUL JOSEPH DOMINOWSKI
JOHN MORGAN HARDHAM
JAMES ALAN JACKSON
CYRIL GERARD GAY
LUIS LEANDRO RODRIGUEZ
PETER WILLIAM KRUG
AIDA ELIZABETH RIEDER
Application Number:
JP2020157185A
Publication Date:
January 07, 2021
Filing Date:
September 18, 2020
Export Citation:
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Assignee:
ZOETIS SERVICES LLC
US SECRETARY OF AGRICULTURE THE
International Classes:
A61K39/135; A61K39/39; A61P31/12; A61P37/04
Domestic Patent References:
JP2013504583A2013-02-07
JP2002534480A2002-10-15
JP2006523189A2006-10-12
JP2011525911A2011-09-29
Foreign References:
WO2014077825A12014-05-22
CN103083663A2013-05-08
Other References:
CAO YIMEI: "ADJUVANTS FOR FOOT-AND-MOUTH DISEASE VIRUS VACCINES: RECENT PROGRESS", EXPERT REVIEW OF VACCINES, vol. VOL:13, NR:11, JPN5018000001, 1 November 2014 (2014-11-01), GB, pages 1377 - 1385, ISSN: 0004812495
BUCAFUSCO, DANILO ET AL., VIROLOGY, vol. 476, JPN6019040152, February 2015 (2015-02-01), pages 11 - 18, ISSN: 0004589306
Attorney, Agent or Firm:
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi
Reiko Izumiya