Title:
ANALYSIS OF LIPOPROTEIN BY DIFFERENTIAL CHARGED PARTICLE MOBILITY
Document Type and Number:
Japanese Patent JP2021059558
Kind Code:
A
Abstract:
To provide an apparatus and a method for preparing lipoproteins including HDL, LDL, Lp(a), IDL, and VLDL, from a biological sample for diagnostic purposes utilizing differential charged particle mobility analysis methods.SOLUTION: Disclosed is a system for analyzing size distribution of lipoproteins, where the system collects, via an ion mobility analyzer configured to receive samples for differential charged-particle mobility analysis, differential ion mobility data for a sample having one or more lipoproteins, the system determines, using the differential ion mobility data, a lipoprotein particle size distribution for one or more lipoproteins, where determining the lipoprotein particle size distribution comprises determining a best fit of the differential ion mobility data for a set of one or more regions of lipoprotein particle sizes for analysis to one or more decaying exponential functions over the regions for analysis.SELECTED DRAWING: None
Inventors:
MICHAEL P CAULFIELD
RICHARD E REITZ
LI SHUGUANG
GLORIA KWANGJA LEE
RONALD KRAUSS
PATRICIA J BLANCHE
W HENRY BENNER
EARL CORNELL
RICHARD E REITZ
LI SHUGUANG
GLORIA KWANGJA LEE
RONALD KRAUSS
PATRICIA J BLANCHE
W HENRY BENNER
EARL CORNELL
Application Number:
JP2020203971A
Publication Date:
April 15, 2021
Filing Date:
December 09, 2020
Export Citation:
Assignee:
QUEST DIAGNOSTICS INVEST INC
International Classes:
C07K1/14; C07K14/775; G01N33/92
Domestic Patent References:
| JP2005509860A | 2005-04-14 | |||
| JPH08327597A | 1996-12-13 | |||
| JP2005208063A | 2005-08-04 |
Foreign References:
| US5578460A | 1996-11-26 |
Attorney, Agent or Firm:
Seiji Ohno
Yuko Matsuniya
Yuko Matsuniya