Title:
HETERODIMERIC FC FUSED CYTOKINES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME
Document Type and Number:
Japanese Patent JP2021088601
Kind Code:
A
Abstract:
To provide heterodimeric Fc fused cytokines and pharmaceutical compositions comprising the same.SOLUTION: The invention relates to a heterodimeric Fc fused cytokine and a pharmaceutical composition comprising the same, where the heterodimeric Fc fused protein comprises a first Fc region and a second Fc region of a Fc region pair of an immunoglobulin, and a biologically active protein whose subunit is linked to at least one end of the N terminus or C terminus of the first Fc region and/or the second Fc region, where the first and second Fc regions are modified to promote formation of heterodimer.SELECTED DRAWING: None
Inventors:
KIM YONG SUN
JUNG KEUNOK
HA JI HEE
KIM YE JIN
CHOI DONG KI
CHOI HYE JI
JUNG KEUNOK
HA JI HEE
KIM YE JIN
CHOI DONG KI
CHOI HYE JI
Application Number:
JP2021033816A
Publication Date:
June 10, 2021
Filing Date:
March 03, 2021
Export Citation:
Assignee:
UNIV AJOU IND ACADEMIC COOP FOUND
International Classes:
C07K14/52; A61K38/20; A61K38/24; A61K45/00; A61K47/68; A61P35/00; A61P43/00; C07K16/00; C07K19/00
Domestic Patent References:
| JP2001525423A | 2001-12-11 | |||
| JP2016506377A | 2016-03-03 |
Other References:
THE JOURNAL OF IMMUNOLOGY, vol. 160, JPN6020033063, 1998, pages 6195 - 6203, ISSN: 0004779642
JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 285, no. 25, JPN6020033065, 2010, pages 19637 - 19646, ISSN: 0004779643
JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 285, no. 25, JPN6020033065, 2010, pages 19637 - 19646, ISSN: 0004779643
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto