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Title:
6-MEMBERED AZA-HETEROCYCLE-CONTAINING DELTA-OPIOID RECEPTOR MODULATING COMPOUNDS, METHODS OF USING THAT COMPOUND, AND METHODS OF MAKING THAT COMPOUND
Document Type and Number:
Japanese Patent JP2021138744
Kind Code:
A
Abstract:
To provide compounds for modulating the activity of delta opioid receptor, and methods for treating pain, migraines, headaches, depression, Parkinson's disease, anxiety, and overactive bladder using the compounds.SOLUTION: The present invention employs a compound in the figure or the like.SELECTED DRAWING: Figure 1-1

Inventors:
AIMEE CROMBIE SPEERSCHNEIDER
DENNIS SHINJI YAMASHITA
PHILIP MICHAEL PITIS
MICHAEL JOHN HAWKINS
LIU GUODONG
TAMARA ANN MISKOWSKI DAUBERT
CATHERINE C K YUAN
ROBERT BORBO KARGBO
ROBERT JASON HERR
DONNA ROMERO
GREGORY J PACOFSKY
Application Number:
JP2021096263A
Publication Date:
September 16, 2021
Filing Date:
June 09, 2021
Export Citation:
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Assignee:
TREVENA INC
International Classes:
C07D241/04; A61K31/454; A61K31/4545; A61K31/5377; A61P7/12; A61P13/10; A61P25/02; A61P25/04; A61P25/06; A61P25/16; A61P25/22; A61P25/24; A61P25/30; C07D211/22; C07D401/14; C07D403/12; C07D403/14; C07D413/12
Domestic Patent References:
JP2014532640A2014-12-08
JP2009520018A2009-05-21
JPH01313461A1989-12-18
Foreign References:
WO2001032178A12001-05-10
WO2013115163A12013-08-08
Other References:
MOLECULAR PHARMACOLOGY, vol. 85, no. 2, JPN6022037148, 2014, pages 237 - 248, ISSN: 0004868300
DATABASE CAPLUS [ONLINE]: CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO ISA., JPN7022004244, 1999, ISSN: 0004868301
ACTA CHEMICA SCANDINAVICA, vol. 50, no. 2, JPN6022037149, 1996, pages 164 - 169, ISSN: 0004868302
JOURNAL OF CHROMATOGRAPHY B: BIOMEDICAL SCIENCES AND APPLICATIONS, vol. 734, no. 2, JPN6022037151, 1999, pages 229 - 246, ISSN: 0004868303
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi