Title:
【発明の名称】血漿を高分子量の流れを低分子量の流れとに分離する方法
Document Type and Number:
Japanese Patent JP2594786
Kind Code:
B2
Abstract:
An ultrafiltration device comprising hollow fibers or thin channels through which ultrafiltration of blood plasma is effected is operated under conditions of tangential flow and low conversion. A recirculation stream of high molecular weight fraction of the liquid stream is fed to the device and a permeate stream from the device is recovered. The optimum module aspect ratio is designed and the corresponding maximum shear rate of incoming liquid is specified and controlled so as to provide maximum separation efficiency (selectivity and flux) allowing for separation between species of similar size or molecular weight. Shear rate is controlled by controlling the recirculation stream flow rate. The ratio of the transmembrane pressure at the channel outlet to the transmembrane pressure at the channel inlet resulting from the optimal design and operation is also specified.
Inventors:
Antoni Jei Deireo
Gaston de los Reyes
Gaston de los Reyes
Application Number:
JP2651887A
Publication Date:
March 26, 1997
Filing Date:
February 09, 1987
Export Citation:
Assignee:
Millipore Co-Poration
International Classes:
B01D61/00; A61M1/34; B01D61/14; (IPC1-7): A61M1/34
Domestic Patent References:
| JP6099263A | ||||
| JP59115050A |
Attorney, Agent or Firm:
Motohiro Kurauchi (1 outside)