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Title:
【発明の名称】閉経前の女性に対するホルモン置換治療および避妊保護のための医薬組成物
Document Type and Number:
Japanese Patent JP2645510
Kind Code:
B2
Abstract:
Disclosed herein is a method of providing hormonal replacement therapy and contraception for a pre-menopausal woman, which comprises administering to a pre-menopausal woman in need thereof a combination dosage form of an estrogen selected from 0.5-2.0 mg. of 17 beta -estradiol, 0.008-0.030 mg. of ethinyl estradiol, and 0.015-0.060 mg. of mestranol; and a progestogen selected from 0.025-0.100 mg. of levonorgestrel, 0.010-0.070 mg. of gestodene, 0.025-0.100 mg. of desogestrel, 0.025-0.100 mg. of 3-ketodesogestrel, and 0.085-0.35 mg. of norethindrone, said combination dosage form being administered for 23-25 days beginning at day one of the menstrual cycle, followed by 2-5 pill-free or blank pill days, for a total of 28 days in the administration cycle. The preferred dosage form of the invention is a combination of 1 mg. of 17 beta -estradiol and 0.050 or 0.075 mg. of levonorgestrel. The preferred administration cycle of the invention is administration of the combination dosage form for the first 24 days of the menstrual cycle and no dosage form for the last 4 days of the menstrual cycle.

Inventors:
ATSUPUTON JII BAAJINIA
Application Number:
JP50448087A
Publication Date:
August 25, 1997
Filing Date:
July 10, 1987
Export Citation:
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Assignee:
AMERIKAN HOOMU PURODAKUTSU CORP
International Classes:
A61K31/565; A61P13/02; A61P15/00; A61P43/00; C07J1/00; (IPC1-7): A61K31/565; A61K31/565
Domestic Patent References:
JP56140914A
JP60169419A
Other References:
【文献】欧州公開136011(EP,A1)
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)