Title:
【発明の名称】磁気共鳴画像診断用造影剤の製造方法
Document Type and Number:
Japanese Patent JP2655004
Kind Code:
B2
Abstract:
A diagnostic imaging agent is provided for use in conjunction with a magnetic resonance imaging system for the imaging of spacial oxygen distribution in tissue. The imaging agent is comprised of a complex of oxygen-17, a biologically acceptable liquid carrier, such as a perfluorinated compound, and an emulsifying agent, and wherein the agent has an average particle size of less than about 0.6 microns, and an ionic composition essentially equal to that of blood. Useful information can be obtained, and in certain instances, therapy administered, by a non-envasive imaging technique relative to tissue perfusion by 19F-NMR (imaging of 19F) and oxygen utilization by 1H-NMR (imaging of H217O as a metabolite).
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Inventors:
GAPUTEI PURADEIIPU
ARAI TOSHUKI
RASUKAA SHIGUMANDO II
ARAI TOSHUKI
RASUKAA SHIGUMANDO II
Application Number:
JP50887689A
Publication Date:
September 17, 1997
Filing Date:
August 16, 1989
Export Citation:
Assignee:
GAPUTEI PURADEIIPU
ARAI TOSHUKI
RASUKAA SHIGUMANDO II
ARAI TOSHUKI
RASUKAA SHIGUMANDO II
International Classes:
A61K49/00; A61K49/18; G01R33/28; G01R33/465; (IPC1-7): A61K49/00; G01R33/28
Domestic Patent References:
| JP59196448A | ||||
| JP62228010A |
Attorney, Agent or Firm:
Shinichiro Takatori