Title:
【発明の名称】アミノメチル‐クロマン及び‐チオクロマン化合物
Document Type and Number:
Japanese Patent JP2673024
Kind Code:
B2
Abstract:
The present invention includes compounds represented by the formula: wherein X is O or S; R1 and R2 are independently selected from the group consisting of hydrogen, hydroxy, halo, loweralkoxy, thioalkoxy and loweralkyl; or R1 and R2 taken together can form a methylenedioxy or ethylenedioxy bridge; R3 is loweralkyl; R4 is selected from wherein Y is O or S, R6 is hydrogen, methoxy or halo and m is 0 or 1; R5 is hydrogen, loweralkyl, phenyl or substituted phenyl wherein the phenyl ring is substituted with one, two or three substituents independently selected from loweralkyl, halo, hydroxy, loweralkoxy, amino and thioalkoxy; and R8 is hydrogen or R3 and R8 taken together form a pyrrolidine ring; or a pharmaceutically acceptable salt thereof.
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Inventors:
Dee Bernard Deis, Jiyon Francis
Allendsen, David Lloyd
Zere, Robert Edward
Allendsen, David Lloyd
Zere, Robert Edward
Application Number:
JP50197489A
Publication Date:
November 05, 1997
Filing Date:
January 13, 1989
Export Citation:
Assignee:
Abbot Laboratories
International Classes:
A61K31/35; A61K31/352; A61K31/38; A61K31/382; A61K31/40; A61K31/4025; A61P25/02; A61P25/24; A61P25/26; C07D311/04; C07D311/16; C07D311/58; C07D311/60; C07D311/64; C07D335/06; C07D403/06; C07D405/06; C07D405/12; C07D405/14; C07D407/12; C07D409/06; C07D409/12; C07D409/14; C07D493/04; C07D495/04; (IPC1-7): C07D311/58; A61K31/35; A61K31/38; A61K31/40; C07D311/60; C07D335/06; C07D405/06; C07D407/12; C07D409/12; C07D409/14; C07D493/04
Attorney, Agent or Firm:
Yoshio Kawaguchi (4 outside)