Title:
【発明の名称】液滴内の液交換方法
Document Type and Number:
Japanese Patent JP2699493
Kind Code:
B2
Abstract:
PURPOSE:To easily exchange liquid and to obtain a single crystal of a biological polymer by placing two nozzles to face each other in a distance of a diameter of a liquid drop, discharging a liquid from one nozzle to form a drop, and sucking the liquid in the liquid drop from the other nozzle. CONSTITUTION:A discharging nozzle 2 to discharge a liquid and a sucking nozzle 3 to such a liquid are so put to face each other while keeping a distance of about a diameter of a liquid drop in a necessary size for liquid exchange of a liquid drop to stop growing of a crystal of a biopolymer. Then, a solution which is a mixture of protein solution and an agent to make the solution water- insoluble is discharged from the discharging nozzle 2 to form a liquid drop 1 in a prescribed size and the drop is held by bringing the sucking nozzle 3 into contact with the other end of the drop. By this, the liquid in the liquid drop can be exchanged easily and a crystal grown under the very low gravity is recovered as it is. As a result, crystal structures of biopolymers such as proteins, etc., are determined accurately.
Inventors:
Asano Koji
Takafumi Hataya
Shozo Fujita
Kotaro Oka
Takafumi Hataya
Shozo Fujita
Kotaro Oka
Application Number:
JP30525688A
Publication Date:
January 19, 1998
Filing Date:
November 30, 1988
Export Citation:
Assignee:
富士通株式会社
International Classes:
C12M1/00; B01J19/00; C07K1/00; C07K1/14; C07K16/00; C12N9/00; C30B29/58; C30B30/08; (IPC1-7): B01J19/00; C07K1/14; C12N9/00; C30B29/58; C30B30/08
Domestic Patent References:
| JP251488A | ||||
| JP297499A |
Attorney, Agent or Firm:
Teiichi