Title:
【発明の名称】糖尿病発生トランスジェニックマウス
Document Type and Number:
Japanese Patent JP2771493
Kind Code:
B2
Abstract:
Disclosed in this invention is a transgenic nonhuman animal comprising recombinant DNA including a promoter of a gene expressed in pancreatic beta -cells and a heat shock protein 70 gene operatively linked downstream to said promoter. Transgenic mice having non-insulin dependent diabetes characterized by a level of 300 mg/dl of glucose in blood were obtained. This transgenic mouse is useful in the fields of research for development of models of diabetes, identification of the mechanism inducing diabetes, development of therapeutic agents and assays for novel medicines.
Inventors:
JO TEISUN
KIN JUNKI
KIN SHOIRU
KIN JUNKI
KIN SHOIRU
Application Number:
JP30309895A
Publication Date:
July 02, 1998
Filing Date:
November 21, 1995
Export Citation:
Assignee:
JO TEISUN
International Classes:
A01K67/00; A61K48/00; C07H21/04; C07K14/47; C07K14/575; A01K67/027; C07K14/62; C07K19/00; C12N5/00; C12N5/10; C12N15/00; C12N15/09; C12N15/12; C12N15/85; G01N33/48; G01N33/50; C12R1/91; (IPC1-7): C12N15/09; A01K67/027
Domestic Patent References:
| JP8289791A |
Attorney, Agent or Firm:
Takehiko Suzue