【発明の名称】三環式誘導体および薬剤におけるそれらの使用

Title:

【発明の名称】三環式誘導体および薬剤におけるそれらの使用

Document Type and Number:

Japanese Patent JP2793914

Kind Code:

B2

Abstract:

Disclosed are compounds of Formula I: (I) or a pharmaceutically acceptable salt or solvate thereof, wherein: R4 is alkenyl, alkoxy, or -OH. Also disclosed are pharmaceutical compositions containing compounds of Formula I, methods for inhibiting tumor necrosis factor- alpha , and methods for treating septic shock, inflammation, or allergic disease.

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Inventors:

TEIN HOORIN SHII
FURIARII RICHAADO JEI
TOMU UINGU SHII
RII JOO EFU
SEIRU BERA EI

Application Number:

JP51622295A

Publication Date:

September 03, 1998

Filing Date:

December 05, 1994

Export Citation:

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Assignee:

SHEERINGU PURAU CORP

International Classes:

A61K31/135; A61K31/165; A61K31/335; A61K31/445; A61K31/451; A61P29/00; A61P37/08; C07C211/31; C07C211/32; C07C215/20; C07C215/38; C07C217/16; C07D211/14; C07C217/48; C07C233/05; C07C233/13; C07C235/34; C07D211/70; C07D313/12; (IPC1-7): C07C211/31; A61K31/135; A61K31/165; A61K31/335; A61K31/445; C07C215/20; C07C217/16; C07C233/05; C07C235/34; C07D211/14; C07D211/70; C07D313/12

Domestic Patent References:

JP5132477A

Attorney, Agent or Firm:

Shusaku Yamamoto

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