Title:
【発明の名称】リポソームおよび脂質複合体組成物の調製
Document Type and Number:
Japanese Patent JP2798302
Kind Code:
B2
Abstract:
Liposome and lipidic particle formulations of compounds are prepared by dissolving in a solution of liposome-forming lipids in an aprotic solvent such as DMSO, optionally containing a lipid-solubilizing amount of a lower alkanol, and injecting the resulting solution into an aqueous solution. The resulting liposome or lipidic particle suspension may then be dialyzed or otherwise concentrated. This method is particularly useful for compounds which are poorly-soluble in aqueous solution, but is generally useful for any compound or combination of compounds which can be dissolved in the aprotic solvent or aprotic solvent/lower alkanol mixture.
Inventors:
Zocca Jr., Francis C.
Application Number:
JP50611490A
Publication Date:
September 17, 1998
Filing Date:
March 28, 1990
Export Citation:
Assignee:
The Regents of the University of California
International Classes:
A61K9/10; A61K9/127; A61K9/16; A61K31/135; A61K31/28; A61K31/415; A61K31/425; A61K31/70; A61K38/00; A61K38/21; A61K38/22; A61K38/43; A61K38/55; A61K47/48; A61K49/00; A61K51/00; (IPC1-7): A61K9/127
Attorney, Agent or Firm:
Atsushi Nakajima (2 outside)