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Title:
【発明の名称】多相組成物の調製方法
Document Type and Number:
Japanese Patent JP2873253
Kind Code:
B2
Abstract:
The instant invention relates to methods of preparing and stabilizing complex multiphase compositions that include distinct phases of water, gel, liquid crystal or oil and perfluoropolyether dispersed in a continuous phase of a silicone fluid. In particular, the present invention relates to a method of preparing a stable multiphase composition comprising the steps of mixing an aqueous solution of a water-soluble polymeric emulsifier, a silicone-based emulsifier and an oleophobic, hydrophobic silicone fluid in amounts effective to form a stable water-in-silicone emulsion; mixing the water-in-silicone emulsion with a hydrophilic gel comprising a homogeneous mixture of water and a sufficient amount of at least one viscosity-enhancing, water-soluble polymer, the emulsion and gel being combined in amounts effective to form a dispersion in which the gel is dispersed in the emulsion; and adding to the dispersion an oil or a thermotropic liquid crystal and a perfluoropolyether in amounts effective to form a stable, multiphase composition comprising a continuous phase of silicone fluid and independent, polydisperse phases of water, gel, oil or liquid crystal and perfluoropolyether.

Inventors:
RAHANASU KONSUTANTEINOSU EMU
KIIRAA TOREISHII ENU
BAKUA ANDORYUU JEI
CHOKA JOOJI
Application Number:
JP51947493A
Publication Date:
March 24, 1999
Filing Date:
April 28, 1993
Export Citation:
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Assignee:
ESUTEII ROODAA INC
International Classes:
A61K8/00; A61K8/03; A61K8/06; A61K9/107; A61K8/41; A61K8/70; A61K8/72; A61K8/73; A61K8/81; A61K8/89; A61K8/891; A61K9/113; A61K9/127; A61Q19/00; B01J13/00; C08L83/04; C09K19/36; C09K19/54; C09K23/52; (IPC1-7): B01J13/00; A61K7/00; A61K9/107
Attorney, Agent or Firm:
Takashi Ishida (3 others)



 
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