Title:
【発明の名称】血管作動性バソトシン誘導体
Document Type and Number:
Japanese Patent JP2957275
Kind Code:
B2
Abstract:
PCT No. PCT/SE91/00154 Sec. 371 Date Sep. 23, 1992 Sec. 102(e) Date Sep. 23, 1992 PCT Filed Feb. 26, 1991 PCT Pub. No. WO91/13092 PCT Pub. Date Sep. 5, 1991.The present invention relates to new vasotocin derivatives with prolonged activity compared to previous vasotocin derivatives. In particular, the vasotocin derivatives of the present invention are of the formula (I) wherein Hmp is a 2-hydroxy-3-mercaptopropionic acid residue, Z is Phe or Tyr, Y is Hgn or Hci, X is a residue of the formula wherein Q is H, alanyl or L-2-aminobutyryl and n is 1, 2 or 3. The present invention also relates to pharmaceutical compositions containing these vasotocin derivatives.
Inventors:
AURERU KAARUUYOHAN
MERIN PERU
NIRUSON ANDERUSU
TOROINARU IERUJII
MERIN PERU
NIRUSON ANDERUSU
TOROINARU IERUJII
Application Number:
JP50503091A
Publication Date:
October 04, 1999
Filing Date:
February 26, 1991
Export Citation:
Assignee:
FUERINGU AB
International Classes:
A61K31/00; A61K38/095; A61K38/12; A61P5/28; A61P9/02; C07K7/00; C07K7/02; C07K7/06; C07K7/16; C07K7/52; A61K38/00; A61K; C07K; (IPC1-7): C07K7/16; A61K31/00; A61K38/11
Other References:
【文献】国際公開89/3393(WO,A1)
Attorney, Agent or Firm:
Kazuo Sato (2 outside)