Title:
【発明の名称】エストロゲン感受性疾患の治療のための組合せ療法
Document Type and Number:
Japanese Patent JP2959838
Kind Code:
B2
Abstract:
A method of treatment of breast and endometrial cancer in susceptible warm-blooded animals may include inhibition of ovarian hormonal secretion by surgical (ovariectomy) or chemical (use of an LHRH agonist, e.g. [D-Trp6, des-Gly-NH210]LHRH ethylamide or antagonist) as part of a combination therapy comprising administering an antiestrogen together with at least one compound selected from the group consisting of an androgen, a progestin, at least one inhibitor of sex steroid formation, especially 17 beta -hydroxysteroid dehydrogenase and aromatase activity, at least one inhibitor of prolactin secretion, one inhibitor of growth hormone secretion and one inhibitor of ACTH secretion. Pharmaceutical compositions useful for such treatment and pharmaceutical kits containing such composition are disclosed.
Inventors:
RABURI FUERUNAN
Application Number:
JP50485890A
Publication Date:
October 06, 1999
Filing Date:
March 09, 1990
Export Citation:
Assignee:
ANDORUSHERUSHU INC
International Classes:
A61K31/00; A61K31/047; A61K31/16; A61K31/445; A61K31/48; A61K31/495; A61K31/56; A61K31/565; A61K31/13; A61K31/57; A61K31/575; A61K38/00; A61K38/04; A61K45/00; A61K45/06; A61P5/32; A61P13/00; A61P13/02; A61P15/00; A61P35/00; A61P43/00; C07J1/00; (IPC1-7): A61K45/00; A61K31/00; A61K31/13; A61K31/16; A61K31/48; A61K31/565; A61K38/04
Other References:
【文献】Biological Abstracts,74048182
【文献】Br.J.Cancer,(1982),46(1),p30~34
【文献】The Merck Imdex,TENTH EDITION,2799.Danazolの項
【文献】Br.J.Cancer,(1982),46(1),p30~34
【文献】The Merck Imdex,TENTH EDITION,2799.Danazolの項
Attorney, Agent or Firm:
Hisami Fukami (4 outside)