Title:
【発明の名称】新規化合物、その製法及びそれを含む医薬組成物
Document Type and Number:
Japanese Patent JP2979235
Kind Code:
B2
Abstract:
beta -Lactam compounds of the formula (Ia) including pharmaceutically acceptable salts and in vivo hydrolysable esters, processes for their preparation and their use as antibiotics: wherein R<1> is hydrogen, methoxy or formamido; R<2> is an acyl group, in particular that of an antibacterially active cephalosporin; CO2R<6> is a carboxy group or a carboxylate anion; R<3> is a gamma -lactone ring optionally containing an endocyclic double bond, which ring is optionally substituted at any carbon atom by alkyl, dialkylamino, alkoxy, hydroxy, halogen or aryl, which in the case of more than one substituent may be the same or different, or is optionally di-substituted at two adjacent carbon atoms, which are available for substitution, to form an aromatic fused bicyclic system; and X is S, SO, SO2, O or CH2.
Inventors:
JON HAAGURIIBUSU BEITOSON
JOOJI BAATON
SUTEFUAN KURISUTOFUAA MAACHIN
JOOJI BAATON
SUTEFUAN KURISUTOFUAA MAACHIN
Application Number:
JP8148190A
Publication Date:
November 15, 1999
Filing Date:
March 30, 1990
Export Citation:
Assignee:
FUAIZAA INC
International Classes:
A61K31/00; A61K31/397; A61K31/435; A61K31/4353; A61K31/535; A61K31/5365; A61K31/545; C07D477/00; A61K31/546; A61P31/00; A61P31/04; C07D463/00; C07D498/04; C07D501/18; C07D501/20; C07D501/24; C07D501/56; C07D505/00; A61K; C07D; (IPC1-7): C07D501/20; A61K31/00; A61K31/435; A61K31/535; A61K31/545; C07D463/00; C07D501/20; C07D505/00
Domestic Patent References:
| JP5841886A |
Attorney, Agent or Firm:
Akizawa Masamitsu