Title:
【発明の名称】エリスロマイシンおよびアジスロマイシンの3”-デスメトキシ誘導体
Document Type and Number:
Japanese Patent JP3083102
Kind Code:
B2
Abstract:
A compound having the formula (IV) wherein Z is CH2-N(CH3), N(CH3)-CH2, or R1 and R2 are selected from 1) one of R1 and R2 is OH and the other of R1 and R2 is (C1-C6)alkyl, (C2-C6)alkenyl, or phenyl, with the proviso that Z is not CO; 2) one of R1 and R2 is H and the other of R1 and R2 is NR5R6 wherein R5 and R6 are independently selected from H and (C1-C6)alkyl, or is OR7 wherein R7 is H or (C1-C6)alkyl; and 3) R1 and R2 together form an oxo or oxime group; R3 and R4 are each hydroxyl or together form a carbonate or thiocarbonate group; and pharmaceutically acceptable salts thereof.
Inventors:
Bin, Vinway Vu
Application Number:
JP52279595A
Publication Date:
September 04, 2000
Filing Date:
February 02, 1995
Export Citation:
Assignee:
Pfizer Inc.
International Classes:
A61K31/70; A61K31/7042; A61K31/7048; A61K31/7052; A61P31/04; C07H17/00; C07H17/08; (IPC1-7): C07H17/08; C07H17/00
Domestic Patent References:
| JP64110694A | ||||
| JP60231691A | ||||
| JP5255375A | ||||
| JP140039B2 | ||||
| JP6152837B2 |
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)