Title:
【発明の名称】立体特異的なGABA-T阻害剤のラセミ混合物の酵素的分割
Document Type and Number:
Japanese Patent JP3213717
Kind Code:
B2
Abstract:
The present invention relates to the enzymatic resolution of a racemic mixture of stereospecific, pharmaceutically useful in vivo inhibitors of gamma -aminobutyric acid transaminase (GABA-T), specifically gamma -ethynyl GABA, gamma -vinyl GABA and gamma -allenyl GABA using penicillin acylase (PA).
Inventors:
Margoline, Alexey El.
Application Number:
JP50445294A
Publication Date:
October 02, 2001
Filing Date:
June 15, 1993
Export Citation:
Assignee:
Merrell Pharmaceuticals, Inc.
International Classes:
C12P13/00; C12P41/00; (IPC1-7): C12P41/00
Attorney, Agent or Firm:
Katsuro Sasai