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Title:
【発明の名称】コカイン受容体結合リガンド
Document Type and Number:
Japanese Patent JP3350049
Kind Code:
B2
Abstract:
PCT No. PCT/US91/05553 Sec. 371 Date Mar. 23, 1993 Sec. 102(e) Date Mar. 23, 1993 PCT Filed Aug. 9, 1991 PCT Pub. No. WO92/02260 PCT Pub. Date Feb. 20, 1992.3 beta -[4-iodophenyl]-tropan-2 beta -carboxylic acid methyl ester tartrate is a high affinity binding ligand for cocaine receptors in mammalian brains. It and its congeners may be employed for imaging and other brain scanning techniques that allow the determination of the presence of cocaine receptors, such as dopamine and serotonin transporters and the like.

Inventors:
Cooher Michael J.
Carol frank ivy
Boja Joan W
Liuin Anita H
Abraham Philip
Application Number:
JP51507991A
Publication Date:
November 25, 2002
Filing Date:
August 09, 1991
Export Citation:
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Assignee:
Research Triangle Institute
International Classes:
A61K51/00; C07D451/02; C07F7/22; G01N33/50; (IPC1-7): C07D451/02; A61K51/00; G01N33/50
Other References:
【文献】米国特許3813404(US,A)
Attorney, Agent or Firm:
Kazuo Sato (3 others)