Title:
【発明の名称】三環性ピロール若しくはピラゾール誘導体
Document Type and Number:
Japanese Patent JP3410478
Kind Code:
B2
Abstract:
A tricyclic pyrrole or pyrazole derivative represented by the following general formula (I), or a pharmaceutically acceptable salt thereof, which shows strong affinity and selectivity for the 5-HT2C receptor and is useful for the treatment of central nervous system diseases such as sexual disorders, eating disorders, anxiety, depression and sleeping disorders. (In the above formula, each symbol means as follows; Y ring: an unsaturated five-membered ring which may have 1 to 3 of one or more types of hetero atom(s) each selected from the group consisting of a nitrogen atom, an oxygen atom and a sulfur atom or an unsaturated six-membered ring having 1 or 2 nitrogen atom(s), X: a bond or a carbon atom, @ : a double bond or a single bond, V: a nitrogen atom or a group represented by a formula CH, and A: a straight or branched lower alkylene group which may be substituted with a halogen atom or a cycloalkyl group.)
Inventors:
Kyoichi Maeno
Kenichi Sada
Hideki Kubota
Itsuro Shimada
Tetsuya Kimizuka
Shuichi Sakamoto
Bunichi Wanibuchi
Kenichi Sada
Hideki Kubota
Itsuro Shimada
Tetsuya Kimizuka
Shuichi Sakamoto
Bunichi Wanibuchi
Application Number:
JP50209799A
Publication Date:
May 26, 2003
Filing Date:
June 11, 1998
Export Citation:
Assignee:
Yamanouchi Pharmaceutical Co., Ltd.
International Classes:
A61K31/381; A61K31/415; A61K31/4162; C07D231/54; C07D491/04; C07D491/048; C07D495/04; C07D498/04; C07D513/04; (IPC1-7): C07D231/54; A61K31/40; A61K31/415; A61K31/42; A61K31/425; A61K31/47; A61K31/55; A61P15/10; A61P25/00; A61P25/20; A61P25/22; A61P25/24; C07D471/04; C07D491/048; C07D495/04; C07D498/04; C07D513/04
Domestic Patent References:
| JP7149723A | ||||
| JP859623A |
Other References:
【文献】国際公開95/017405(WO,A1)
Attorney, Agent or Firm:
Shozo Nagai (2 outside)