Title:
【発明の名称】抗炎症剤として有用なジヒドロベンゾピランおよび関連化合物
Document Type and Number:
Japanese Patent JP3454832
Kind Code:
B2
Abstract:
PCT No. PCT/US97/09945 Sec. 371 Date Dec. 7, 1998 Sec. 102(e) Date Dec. 7, 1998 PCT Filed Jun. 6, 1997 PCT Pub. No. WO97/46548 PCT Pub. Date Dec. 11, 1997A compound having structure (1) wherein (a) X is selected from the group consisting of O, S, SO, or SO2; (b) each Y is independently hydrogen or straight, branched or cyclic alkanyl having from 1 to about 4 carbon atoms, or the two Y's are bonded to form an alkanyl ring having from 3 to about 7 carbon atoms; (c) Z is branched or cyclic alkyl having from 3 to about 10 atoms other than hydrogen; (d) W is O or S; and (e) R is straight, branched or cyclic alkyl or aryl, saturated or mono- or di-unsaturated with double or triple bonds, R having from 1 to about 15 atoms other than hydrogen; pharmaceutical compositions comprising such compounds, and methods of treating inflammation or pain using such compounds.
Inventors:
Janustu, John, Michael.
Johnson, Carl, Randolph.
Senana Yake, Chandra Wansha, Varadara, W.
Johnson, Carl, Randolph.
Senana Yake, Chandra Wansha, Varadara, W.
Application Number:
JP50090698A
Publication Date:
October 06, 2003
Filing Date:
June 06, 1997
Export Citation:
Assignee:
Vanderbilt University
International Classes:
A61K31/00; A61K31/35; A61K31/352; A61K31/353; A61K31/38; A61K31/382; A61P19/00; A61P19/02; A61P29/00; C07D311/04; C07D311/58; C07D335/04; C07D335/06; (IPC1-7): C07D311/04; A61K31/353; A61K31/382; A61P29/00
Attorney, Agent or Firm:
Yoshikazu Tani (2 outside)