Title:
【発明の名称】可溶性サブミクロン粒子上に固定化した抗体による抗原の無作為検出
Document Type and Number:
Japanese Patent JP3484540
Kind Code:
B2
Abstract:
Methods, compositions and articles of manufacture are provided for conducting specific binding assays to determine the concentration or presence of at least one analyte in a sample. At least two dendrimer-reagent preparations with different analyte specificities may be immobilized on a solid phase. Alternatively, at least one dendrimer-reagent preparation having multiple specificities may be immobilized on a solid phase. Immobilization is facilitated by coupling specific binding assay reagents such as polypeptide receptors or analytes with water soluble polymers. Such water soluble polymers, for example star polymers such as dendrimers, provide production advantages of lot-to-lot uniformity and homogeneity, and can enhance sensitivity due to low non-specific binding to the solid phase.
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Inventors:
Mole, fred, third
Charles Farsli
Lynn, Spencer
Thin, plastic tap
Charles Farsli
Lynn, Spencer
Thin, plastic tap
Application Number:
JP52653395A
Publication Date:
January 06, 2004
Filing Date:
April 12, 1995
Export Citation:
Assignee:
Dade, Bering, Incorporated
International Classes:
G01N33/543; G01N33/545; G01N33/547; G01N33/552; (IPC1-7): G01N33/545; G01N33/552
Domestic Patent References:
| JP3231152A | ||||
| JP5506314A |
Other References:
【文献】国際公開94/003774(WO,A1)
Attorney, Agent or Firm:
Michio Akaoka (1 person outside)
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