Title:
細胞表面分子に対する抗体の生産方法
Document Type and Number:
Japanese Patent JP3514759
Kind Code:
B2
Abstract:
Methods for preventing or treating an antibody-mediated disease in a patient are presented, the methods comprising administration of a monoclonal antibody capable of binding to a human CD40 antigen located on the surface of a human B cell, wherein the binding of the antibody to the CD40 antigen prevents the growth or differentiation of the B cell. Monoclonal antibodies useful in these methods, and epitopes immunoreactive with such monoclonal antibodies are also presented.
More Like This:
Inventors:
コンロイ，レアー ビー．
デ ボア，マーク
デ ボア，マーク
Application Number:
JP50350794A
Publication Date:
March 31, 2004
Filing Date:
July 08, 1993
Export Citation:
Assignee:
カイロン コーポレーション
International Classes:
C12N15/02; A61K31/4353; A61K31/436; A61K31/573; A61K38/00; A61K39/395; A61K45/00; A61P1/16; A61P7/06; A61P29/00; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07K14/705; C07K16/00; C07K16/28; C12N5/10; C12N15/06; C12N15/09; C12P21/02; C12P21/08; G01N33/53; G01N33/531; (IPC1-7): C12N15/02; C07K16/28; C12N5/10; C12P21/02; C12P21/08
Other References:
Ｃｅｌｌ．Ｉｍｍｕｎｏｌ．（１９９３−Ａｐｒ−１５），Ｖｏｌ．１４８，Ｎｏ．１，ｐ．１４４−１５６
Ｃｕｒｒ．Ｏｐｉｎ．Ｉｍｍｕｎｏｌ．（１９９２−Ｊｕｎ），Ｖｏｌ．４，Ｎｏ．３，ｐ．３３３−３３７
Ｉｍｍｕｎｏｌｏｇｙ（１９９０−Ａｐｒ．），Ｖｏｌ．６９，Ｎｏ．４，ｐ．５３１−５３５
Ｊ．Ｉｍｍｕｎｏｌ．（１９９２−Ａｐｒ），Ｖｏｌ．１４８，Ｎｏ．８，ｐ．２４１１−２４１６
Ｊ．Ｉｍｍｕｎｏｌ．Ｍｅｔｈｏｄｓ（１９９２−Ｊｕｌｙ−３１），Ｖｏｌ．１５２，Ｎｏ．１，ｐ．１５−２３
Ｓｃｉｅｎｃｅ（１９９２−Ａｕｇ），Ｖｏｌ．２５７，ｐ．７８９−７９５
Ｃｕｒｒ．Ｏｐｉｎ．Ｉｍｍｕｎｏｌ．（１９９２−Ｊｕｎ），Ｖｏｌ．４，Ｎｏ．３，ｐ．３３３−３３７
Ｉｍｍｕｎｏｌｏｇｙ（１９９０−Ａｐｒ．），Ｖｏｌ．６９，Ｎｏ．４，ｐ．５３１−５３５
Ｊ．Ｉｍｍｕｎｏｌ．（１９９２−Ａｐｒ），Ｖｏｌ．１４８，Ｎｏ．８，ｐ．２４１１−２４１６
Ｊ．Ｉｍｍｕｎｏｌ．Ｍｅｔｈｏｄｓ（１９９２−Ｊｕｌｙ−３１），Ｖｏｌ．１５２，Ｎｏ．１，ｐ．１５−２３
Ｓｃｉｅｎｃｅ（１９９２−Ａｕｇ），Ｖｏｌ．２５７，ｐ．７８９−７９５
Attorney, Agent or Firm:
山本 秀策