Title:
連続的に実施しうる、メチオニンまたはメチオニン誘導体の製造方法
Document Type and Number:
Japanese Patent JP3548574
Kind Code:
B2
Abstract:
PCT No. PCT/EP93/02838 Sec. 371 Date May 23, 1995 Sec. 102(e) Date May 23, 1995 PCT Filed Oct. 14, 1993 PCT Pub. No. WO94/08957 PCT Pub. Date Apr. 28, 1994The direct saponification of methionine nitrile obtained from methylmercaptopropionaldehyde, prussic acid and ammonia gives low yields, catalyst and educt losses and unwanted side-products. The aim of the invention is therefore to provide a method which can be carried out without isolating the intermediate products, in particular continuously, and with low losses. The ketone used is recovered in high yields after amide saponification since this liberates the ketone from side-products. In order to recover the ammonia, it is necessary for the ammonia to be substantially freed of ketone, the mixture of ammonia, ketone and water obtained being separated under pressure in a separation column. When the amide is saponified at >/=160 DEG C., amide concentrations of less than 25% by wt. are preferred. Methionine nitrile is produced by treatment with at least 4 equivalents of >/=50% by wt. ammonia at between 40 DEG and 80 DEG C./or between 5 and 60 min. Cyanide residues are destroyed by heating to over 150 DEG C. Methionine is of particular use as a feedstuff, in particular in aqueous solution.
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Inventors:
Haseberg, Hans-Albrecht
Foot Macher, Claus
Lautenberg, Stephan
Petch, Heinrich
Weigel, horst
Foot Macher, Claus
Lautenberg, Stephan
Petch, Heinrich
Weigel, horst
Application Number:
JP50963594A
Publication Date:
July 28, 2004
Filing Date:
October 14, 1993
Export Citation:
Assignee:
Degussa AG
International Classes:
C07C319/20; C07C323/58; (IPC1-7): C07C319/20; C07C323/58
Domestic Patent References:
| JP62132853A |
Attorney, Agent or Firm:
Toshio Yano
Toshiomi Yamazaki
Takuya Kuno
Einzel Felix-Reinhard
Toshiomi Yamazaki
Takuya Kuno
Einzel Felix-Reinhard