Title:
トランスフォーミング成長因子-β(TGF‐β)の免疫抑制効果の治療用アンチセンス-オリゴヌクレオチド類
Document Type and Number:
Japanese Patent JP3600831
Kind Code:
B2
Abstract:
Antisense-oligonucleotides or effective derivatives thereof hybridizing with an area of a gene coding for transforming growth factor-β (TGF-β) comprising the following nucleic acid sequences identified in the sequence listing under SEQ ID NO. 1-56 and 137 or comprising the following nucleic acid sequences identified in the sequence listing under SEQ ID NO. 57 to 136 each of the nucleic acids having a DNA- or RNA-type structure.
Inventors:
Schlingen Jiepen Georg-Ferdinand
Brish wolfgang
Schlingen Siepen Karl-Hermann
Schlingen Diepen Reymar
Bogdern Ulrich
Brish wolfgang
Schlingen Siepen Karl-Hermann
Schlingen Diepen Reymar
Bogdern Ulrich
Application Number:
JP2003188524A
Publication Date:
December 15, 2004
Filing Date:
June 30, 2003
Export Citation:
Assignee:
Biognostic Gesell Shaft Fuer Biomoleculare Diagnostics Mitt Beschlenktel Haftung
International Classes:
A61K31/70; A61K31/7088; A61K48/00; A61P7/00; A61P35/00; C12N15/09; A61P37/04; C07H21/02; C07H21/04; C12N15/113; (IPC1-7): C12N15/09; A61K31/7088; A61P35/00; A61P37/04
Other References:
J.Exp.Med.,Vol.174, pp.925-929 (1991)
Cell Growth & Differentiation, Vol.4,No.2,pp.115-123 (Feb.1993)
Cell Growth & Differentiation, Vol.4,No.2,pp.115-123 (Feb.1993)
Attorney, Agent or Firm:
Toshio Shiozawa
Masazumi Imamura
Masazumi Imamura