Title:
4―メチル―ビフェニル誘導体の製造方法
Document Type and Number:
Japanese Patent JP3604702
Kind Code:
B2
Abstract:
The subject-matter of the invention is a process for the preparation of substituted 4-methylbiphenyls of general formula:in which R is a cyano group or a protected tetrazolyl group of formula:in which R1, situated at the 1 or 2 position of the tetrazolyl group, is a protective group, characterized in that a halobenzene of formula:in which Hal is a halogen atom and R has the same meaning as above, is reacted with a p-tolylmagnesium halide in the presence of a linear or branched polyether and of a catalyst comprising a transition metal.
Inventors:
Arami, Muad
Cailler, Gerard
Castro, Bertrand
Dorumwa, Jean-Robert
Rigue, eric
Cailler, Gerard
Castro, Bertrand
Dorumwa, Jean-Robert
Rigue, eric
Application Number:
JP51435398A
Publication Date:
December 22, 2004
Filing Date:
September 17, 1997
Export Citation:
Assignee:
Sanofi-Aventis
International Classes:
B01J31/22; C07B61/00; C07C253/30; C07C255/50; C07D257/04; (IPC1-7): C07C253/30; B01J31/22; C07B61/00; C07C255/50; C07D257/04
Domestic Patent References:
| JP8231454A |
Attorney, Agent or Firm:
Aoyama Aoi
Mitsuo Tanaka
Mitsuo Tanaka