Title:
補体関連蛋白質および炭水化物よりなる組成物、ならびに該組成物の製法および使用方法
Document Type and Number:
Japanese Patent JP3662021
Kind Code:
B2
Abstract:
The present invention provides compositions comprising at least one complement moiety and at least one carbohydrate moiety, and methods of producing such compositions. In particular, the compositions of the invention comprise complement proteins related to the complement receptor type 1, and further comprise ligands for intercellular molecules, such as selectins. In a preferred embodiment, the compositions comprise a complement-related protein in combination with the Lewis X antigen or the sialyl Lewis X antigen. The compositions of the invention have use in the diagnosis or therapy of disorders involving complement activity and inflammation. Pharmaceutical compositions are also provided for treating or reducing inflammation mediated by inappropriate complement activity and intercellular adhesion.
Inventors:
Ritters House, Charles W.
Tose, Carroll A.
Tose, Carroll A.
Application Number:
JP52569594A
Publication Date:
June 22, 2005
Filing Date:
May 12, 1994
Export Citation:
Assignee:
Urbanto Immunotherapeutics, Inc.
International Classes:
A61P29/00; A61P37/02; A61K38/00; C07K14/705; (IPC1-7): C07K14/705; A61P29/00
Domestic Patent References:
| JP4501502A | ||||
| JP2022297A | ||||
| JP8501773A | ||||
| JP6504065A |
Foreign References:
| WO1992009293A1 |
Attorney, Agent or Firm:
Hidekazu Miyoshi