Title:
免疫原性構成物の製造のための新規シアン化試薬を使った可溶性炭水化物の活性化方法
Document Type and Number:
Japanese Patent JP3828145
Kind Code:
B2
Abstract:
The invention relates to a process for producing an immunogenic construct comprising activating at least one first carbohydrate-containing moiety with CDAP, and covalently joining the activated first moiety to a second moiety. Preferably, the first moiety is a polysaccharide and the second moiety is a protein. Immunogenic constructs are prepared by this process using either direct or indirect conjugation of the first and second moieties.
Inventors:
Wreath, Andrew
Application Number:
JP50989795A
Publication Date:
October 04, 2006
Filing Date:
September 21, 1994
Export Citation:
Assignee:
Henry M. Jackson Foundation For The Advancement Of Military Medicine
International Classes:
A61K39/00; A61K39/385; A61K47/48
Domestic Patent References:
| JP57136528A | ||||
| JP49028031B1 |
Foreign References:
| WO1993015760A1 |
Other References:
Chu C et al., Infect Immun., 1983年 4月,40(1), 245-56
Kohn J et al., Appl Biochem Biotechnol., 1984年,9(3), 285-305
Carpenter A., J Chromatogr. , 1992年 1月 3日,573(1), 132-5
Andersson A et al., Int J Cancer., 1991年 2月 1日,47(3), 439-44
Kohn J et al., Appl Biochem Biotechnol., 1984年,9(3), 285-305
Carpenter A., J Chromatogr. , 1992年 1月 3日,573(1), 132-5
Andersson A et al., Int J Cancer., 1991年 2月 1日,47(3), 439-44
Attorney, Agent or Firm:
Takashi Ishida
Yoshio Yoshio
Masaya Nishiyama
Yoshio Yoshio
Masaya Nishiyama