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Title:
細胞応答をリアルタイムで測定するための装置及び方法
Document Type and Number:
Japanese Patent JP3847791
Kind Code:
B2
Abstract:
An apparatus and method for real-time measurement of a cellular response of a test compound or series of test compounds (303) on a flowing suspension of cells (349), in which a homogeneous suspension of each member of a series of cell types (349) is combined with a concentration of a test compound (303), directed through a detection zone (355), and a cellular response of the living cells is measured in real time as the cells in the test mixture are flowing through the detection zone (355). The apparatus may be used in automated screening of libraries of compounds, and is capable of real-time variation of concentrations of test and standard compounds and generation of dose/response profiles within a short timespan.

Inventors:
Okun, Ilya
Alex, Alex
Application Number:
JP50810598A
Publication Date:
November 22, 2006
Filing Date:
August 01, 1997
Export Citation:
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Assignee:
CALIPER LIFF SCIENCES INCORPORATED
International Classes:
G01N33/483; C12M1/34; G01N33/50; C12M3/02; C12Q1/02; G01N33/15; G01N33/48; G01N33/68; G01N35/00; G01N35/08; G01N35/10
Domestic Patent References:
JP54151895A
JP7505710A
JP3502642A
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Hidemi Matsukura
Yutaka Nagata
Tsutomu Toyama