Title:
インスリン誘導体
Document Type and Number:
Japanese Patent JP3872105
Kind Code:
B2
Abstract:
Insulin derivatives in which a lipophilic group having from 12 to 40 carbon atoms is attached to the alpha -amino group of the N-terminal amino acid in the B-chain or to the carboxy group of the C-terminal amino acid in the B-chain have a protracted profile of action.
Inventors:
Marxen, Yang
Jonathan, Eve
Hubernd, Sbend
Brandt, Jacob
Kurzhals, Peter
Hansen, Pale Hertz
Karlsholm, Niels Christian
Jonathan, Eve
Hubernd, Sbend
Brandt, Jacob
Kurzhals, Peter
Hansen, Pale Hertz
Karlsholm, Niels Christian
Application Number:
JP52799596A
Publication Date:
January 24, 2007
Filing Date:
March 18, 1996
Export Citation:
Assignee:
NOVO NORDISK AKTIE SELSXAB
International Classes:
C12N15/09; A61K38/28; A61P3/10; A61P9/04; C07K14/62; C12P21/02; C12R1/865
Domestic Patent References:
| JP1254699A | ||||
| JP4325088A | ||||
| JP3014764B2 | ||||
| JP5508406A |
Other References:
Journal of Controlled Release,(1992),19,p179-188
Attorney, Agent or Firm:
Takehiko Suzue
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Ryo Hashimoto
Tetsuya Kazama
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Ryo Hashimoto
Tetsuya Kazama