Title:
4-(6-フルオロ-1,2-ベンズイソオキサゾリル)-1-ピペリジニル-プロポキシ-クロメン-4-オン誘導体、その製造、ならびに精神病、精神分裂症、および不安症の治療におけるその使用
Document Type and Number:
Japanese Patent JP3916662
Kind Code:
B2
Abstract:
PCT No. PCT/EP96/01551 Sec. 371 Date Mar. 14, 1997 Sec. 102(e) Date Mar. 14, 1997 PCT Filed Apr. 11, 1996 PCT Pub. No. WO96/32389 PCT Pub. Date Oct. 17, 1996The present invention relates to 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-one derivatives having the formula (I): (I) wherein R is hydrogen or alkyl having 1 to 4 carbon atoms optionally substituted by hydroxyl, as well as their pharmaceutically acceptable addition salts, which are useful in the treatment of psychosis, schizophrenia and anxiety.
Inventors:
Raphael, fogetto
Angrada, Lewis
Jordi, Boros
Ortiz, Jose A.
Sacristan, Aurelio
Castelo, Josep Em.
Angrada, Lewis
Jordi, Boros
Ortiz, Jose A.
Sacristan, Aurelio
Castelo, Josep Em.
Application Number:
JP53071696A
Publication Date:
May 16, 2007
Filing Date:
April 11, 1996
Export Citation:
Assignee:
Fuerrel International, Sociedad Anonima
International Classes:
C07D413/14; A61K31/445; A61P25/18; A61P25/20; A61P25/22
Domestic Patent References:
| JP7501055A | ||||
| JP3188077A | ||||
| JP61197575A | ||||
| JP8510478A |
Other References:
Juan C. Jaen, Dopamine Autoreceptor Agonists as Potential Antipsychotics. 2.(Aminoalkoxy)-4H-1-benzopyran-4-ones, Journal of Medicinal Chemistry, 1991年,Vol.34, No.1, Pages 248-256
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Sadafumi Kobori
Koji Kikawa
Hajime Asamura
Sadafumi Kobori
Koji Kikawa