Title:
三環ラクタム及びサルタム誘導体及びそれらのヒストンデアセチラーゼ阻害剤としての使用
Document Type and Number:
Japanese Patent JP3961955
Kind Code:
B2
Abstract:
A compound of formula (I) wherein A and B are optionally substituted cyclohexenyl or phenyl groups, X is carbonyl or sulfonyl, and Y is 5-7 atoms-linker, is useful as histone deacetylase inhibitors, particularly for inhibiting cell proliferation.
Inventors:
Georges, Guy
Grossman, Adelbert
Mundigur, Olaf
Von der Saar, Wolfgang
The Telkaw, Tim
Grossman, Adelbert
Mundigur, Olaf
Von der Saar, Wolfgang
The Telkaw, Tim
Application Number:
JP2002562728A
Publication Date:
August 22, 2007
Filing Date:
January 24, 2002
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D209/92; A61K31/403; A61K31/428; A61P35/00; A61P35/02; A61P43/00; C07D275/06
Foreign References:
| WO1998055449A1 |
Other References:
Cancer Research, 2000, Vol.60, No.12, pp.3137-3142
JOURNAL OF MEDICINAL CHEMISTRY, 1992, Vol.35, No.4, pp.663-676
JOURNAL OF MEDICINAL CHEMISTRY, 1992, Vol.35, No.4, pp.663-676
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama
Takashi Ishida
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama