Title:
親油性及び両親媒性のフィルム形成性ポリマー組成物、並びに局所用物質送達系中へのそれらの使用及び、物質の皮膚への送達方法
Document Type and Number:
Japanese Patent JP3981410
Kind Code:
B2
Abstract:
A mixture of lipophilic and amphiphilic/hydrophilic film-forming polymers of the formula (I): R(CO)mO-(CH2CHR<1>O)n-[OCNH-Z-NHCO2(CH2CHR<2>O)n']p-OCNH-Z-NHCO2-(CH2C HR<1>O)n-(CO)mR, wherein R represents (i) an alkyl, alkenyl or alkaryl hydrocarbyl group of from 1 to 30 carbon atoms or (ii) a polypropylene oxide group (PPO); R<1> and R<2>, each, independently, represent a hydrogen atom, or a methyl or ethyl group; Z represents a divalent linking hydrocarbyl group; m is 0 or 1; n and n', are each, independently, a positive number; and p is > 0, preferably p is 0 or 1, provide a skin substantive, occlusive moisture barrier covering for skin or hair. The compositions have a moisturizing effect by reducing transepidermal water loss. The lipophilic or amphiphilic or hydrophilic film-forming polymers may be used individually or as mixtures as a delivery system for delivering pharmacological or cosmetic agents to the skin or hair.
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Inventors:
Carlos M, Summer
Closer, Scott F
Closer, Scott F
Application Number:
JP50456797A
Publication Date:
September 26, 2007
Filing Date:
June 27, 1996
Export Citation:
Assignee:
Macrochem Corporation
International Classes:
A61K8/87; A61K8/00; A61K8/11; A61K8/72; A61K9/70; A61K47/34; A61Q5/00; A61Q19/00
Domestic Patent References:
| JP6240133A | ||||
| JP7025738A | ||||
| JP5339130A |
Attorney, Agent or Firm:
Heikichi Odashima
Heigo Odashima
Heigo Odashima